Intensive fish farming has spread of several bacterial
diseases over the years and as a solution more antimicrobials (antibiotics and
drugs) are used. The negative consequences of antibiotic use on public health
have encouraged the development of strict regulations controlling the use of antibiotics
and other drugs. The high numbers of antibiotic-resistant bacteria because of
antibiotic usage provides a threat to aquaculture as they become the source of
the antibiotic resistant gene that stays in the culture.
Bacterial antibiotic resistance and antibiotic residues has
become a matter of concern across the globe, there is a need to develop
alternatives to deal with for bacterial pathogens in aquaculture.
Several alternatives to the use of antibiotics have been
used successfully in aquaculture. The use of probiotics or friendly bacteria to
avoid pathogenic infections in aquatic organisms has been tested in aquaculture.
Several microorganisms has been tested and used as
probiotics in aquaculture research. The most studied are species of lactic acid
bacteria , Bacillus, Pseudomonas, Aeromonas, yeasts, Acinobacter… These
probiotics have been used in different aquatic organisms and have been shown to
be successful, not only for their ability to prevent disease, but also for
improving digestion and growth. Many of these applications have been targeted
at the early stages of development of the aquatic organisms, such as the larval
stages, because these stages are more susceptible to infections.
Some of the proposed mechanisms that provide protection
against pathogens involve the production of inhibitory compounds, competition
for essential nutrients and adhesion sites, the enhancement of disease
resistance and the modulation of host immune responses.
Another alternative treatment is using natural essential
oils and herbal extracts, which are natural components from plants that are
generally recognized as safe substances (GRAS). Due to their antimicrobial
properties, these natural products may constitute alternative prophylactic and
therapeutic agents in aquaculture.
There is still a lot of research going on and huge scope of
development in the area of natural substitutes to increase productivity with sustainable
environment for Aquaculture. To reduce antibiotic use in aquaculture best
practices are to minimize the level of stress on the fish and reduce the chance
of infections requiring antibiotics treatment.
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